Provocation testing in noncardiac chest pain

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Provocation testing in noncardiac chest pain.

The ability to reproduce chest pain and to identify the esophagus as the source of this pain are the major reasons why provocation testing has become standard in the evaluation of patients with noncardiac chest pain. Recent studies that challenge the validity of performing provocation tests have polarized experts into two camps: those who would abandon such testing because of its low sensitivit...

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Noncardiac chest pain.

Noncardiac chest pain (NCCP) affects approximately 1 quarter of the adult population in the United States. The pathophysiology of the disorder remains to be fully elucidated. Identified underlying mechanisms for esophageal pain include gastroesophageal reflux disease (GERD), esophageal dysmotility, and visceral hypersensitivity. Aggressive antireflux treatment has been the main therapeutic stra...

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Treatment of noncardiac chest pain is often difficult because of the heterogeneous nature of the disorder. This condition can stem from gastroesophageal reflux, visceral hyperalgesia, esophageal motility disorders, psychiatric dysfunction, abnormal biomechanical properties of the esophageal wall, sustained esophageal contractions, abnormal cerebral processing of visceral stimulation, or disrupt...

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TO TH E ED ITO R: Noncardiac chest pain (NCCP) is not only a difficult disorder to define but also a heterogenous disorder with many potential causes. Gastroesophageal reflux disease (GERD) represents as one of the most common gastroenterologic causes of NCCP. Seo et al suggested that the prevalence of GERD was 30 percent in young patients with NCCP. In addition, the proton pump inhibitor (PPI)...

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ژورنال

عنوان ژورنال: The American Journal of Medicine

سال: 1992

ISSN: 0002-9343

DOI: 10.1016/0002-9343(92)80058-8